Biological Services- Models Cryopreservation of MHRA Breeding Stock
Medicines and Healthcare products Regulatory Agency · United Kingdom
Key facts
- Estimated value
- £50,000
- Closing date
- 21 Feb 2025
- Contract starts
- 05 Mar 2025
- Contract ends
- 03 Mar 2028
- Procedure
- Open procedure (below threshold)
- Buyer type
- Central government
- Source
- Contracts Finder
Description
Tenders are invited from establishments who have the capabilities to take on all services related to transgenic colony management.
At the MHRA, the Biological Services facility houses two transgenic mouse breeding colonies. These colonies have been specifically bred to support the Poliomyelitis test work implemented by the Science, Research & Innovation Group.
In-bred transgenic mice with the Human Polio receptor gene provides a practical alternative to the use of non-human primates. These lines are used to assess the neurovirulence of polioviruses and immunogenicity/ protection of vaccines and hence play a key role in the global polio activities of the Agency. Both colonies require refresh, as genetic drift has been observed due to multiple unexpected phenotypic changes. We are therefore seeking assistance in the maintenance and refresh of colonies, possibly looking to utilise already frozen stocks of embryos/ sperm.
Additional information: To express interest and participate in the tender, please register and apply via Atamis e-sourcing portal https://health-family.force.com/s/Welcome.
Should Tenderers have any queries, or having problems using the portal, they should contact Helpdesk at:
Phone: 0800 9956035
E-mail: [email protected]
Categories (CPV)
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