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Tenfell
Awarded contract
Published 15 Apr 2024

The Supply of Doxycycline & Placebo for the AFLOAT Trial

UNIVERSITY OF SOUTHAMPTON · South East

Key facts

Contract value
£64,590
Awarded
06 Mar 2024
Contract starts
06 Apr 2024
Contract ends
31 Dec 2027
Procedure
Competitive quotation (below threshold)
Buyer type
Education

Awarded to

SupplierValue
MODEPHARMA LIMITED£64,590

Description

AFLOAT Study - Antibiotics for acute LRTI in Older People AFLOAT is a publicly-funded (NIHR) and academic-sponsored (University of Southampton) Clinical Trial of an Investigational Medicinal Product (CTIMP). Aim: The aim is to assess whether time until all symptoms are rated absent or mild is no worse in those who take placebo vs antibiotics in adults aged 65 and over who are seen in primary care with LRTI and risk factors for complications. Patients with LRTI will be recruited from primary care sites and randomised to receive either Doxycycline (100mg twice a day on the first day and then 100 mg once a day

for 4 days) or matching placebo. The drugs will be identical in taste and appearance and stored in sealed blind-sequence medication containers holding a 5-day supply of either doxycycline or placebo.

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