Dianthus Nano System
Durham University · United Kingdom
Key facts
- Contract value
- £300,047
- Awarded
- 03 Jan 2023
- Contract starts
- 17 Jan 2023
- Contract ends
- 31 Mar 2025
- Procedure
- Negotiated procedure without prior publication (above threshold)
- Buyer type
- Education
Awarded to
| Supplier | Value |
|---|---|
| NanoTemper Technologies GmbH | £300,047 |
Description
VEAT NOTICE The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities.
The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice.
Additional information: The works, supplies or services can be provided only by a particular economic operator for the following reason:
absence of competition for technical reasons
Explanation: Specific features of the system include the
⢠Measurements are performed in solution (i.e. no immobilisation is required) ⢠Capability to quantify interactions in complex solutions (crude extract, serum) ⢠Means to determine binding constant over a wide range (5 nM - high millimolar) as well as stoichiometry and thermodynamic parameters ⢠Power to work at low nanomolar concentrations ⢠Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard 384 well-plate ⢠Used detection modalities based on two techniques: Spectral shift detection and Temperature-Related Intensity Change (TRIC) ⢠Microfluidics-free ⢠Mass independent measurement i.e., the measurable molecular weight range is from 101-107 Da ⢠Measure up to 384 datapoints per run ⢠Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard SBS 384 well-plate format
Categories (CPV)
- 38540000 Machines and apparatus for testing and measuring
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