Provision of a Single Cell Analysis System

The Faculty of Medicine within the University of Southampton is looking to contract for the provision of a single cell analysis system.

It was once assumed the cell populations were homogeneous, but the latest evidence shows that heterogeneity does in fact exist even at the single cell level. Genomic and transcriptional measurements based on the homogenized cell population are misleading and don’t account for the small but critical changes occurring in the individual cells.

The University of Southampton requires a flexible and quantitative system to assess (epi) genomic, transcriptomic and proteomic, difference at the single cell level, termed ‘omics’ hereafter.

The contract will be evaluated using the following evaluation criteria:

Mandatory Grounds for Exclusion Pass/Fail Discretionary Grounds for Exclusion Discretionary Pass/Fail Insurances Pass/Fail Mandatory Requirements Pass/Fail Technical specification 70% Delivery, Installation, warranty, Service and Training Provisions 15% References 5% Commercial Response 10%

Additional information: Bidders are advised that the estimated value of this contract in its entirety is £214,000.00 GBP (excluding VAT). This value is intended to reflect the initial contract period of five years PLUS the value of any contract extensions up to a total contract term of four years.

The estimated contract value for the initial contract period is £214,000 GBP (excluding VAT)

The In-Tend Portal: The University is utilising an electronic tendering tool (In-Tend: https://in-tendhost.co.uk/universityofsouthampton) to manage this procurement and to communicate with bidders. All documentation in relation to this tender can be downloaded from the In-Tend portal.

Bidders are advised that there will be no hard copy documents issued to organisations and all communications with the University including the submission of PQQ and/or Invitation to Tender Responses will be conducted via the In-Tend portal. Regular monitoring of the portal is the responsibility of the bidder.

If you are not already registered as a supplier with the University of Southampton, you will need to register in In-Tend in order to access the tender documentation.

Once you have logged in as a supplier: click on ‘Tenders’; locate the relevant project; and click ‘View Details’. Once you are in the project screen, you will be able to register your company against the project and access all documentation by clicking ‘Express Interest’.

Bidders are advised that formal expressions of interest in the project must be by way of completion and return of the relevant Pre-Qualification (if applicable) or Invitation to Tender documents via the In-Tend portal.

Further instructions for the submission of Invitation to Tender responses are below. To submit your return, please follow the instructions below: 1. Log In 2. Click ‘Tenders’ 3. Locate the relevant project 4. View Details 5. Click on the tab relating to the relevant project stage (e.g. ‘Invitation to Tender’) 6. Click on the ‘Attach Documents’ button and upload your return. 7. Check ALL your response documents are uploaded and displayed in the “My Tender Return” panel. The system will only permit your organisation to make one return. 8. Click the red “Submit Return” button.

Please note that, to preserve the integrity of the tendering procedure, all queries must made be via the correspondence function within the In-Tend portal.

In accordance with Regulation 50, paragraph (2) of the Public Contracts Regulations 2015 and subject to Article 5 and Annex 5, Part D (13) of Directive 2014/24/EU of the European Parliament and of the Council (if applicable), the University intends to publish the value of any resulting contract at the award stage, and reserves the right to do so. By submitting a tender response, bidders are consenting to publication of this information unless otherwise agreed in advance with the University.

Due to the nature of this service, it has been deemed unsuitable for division into lots.

Is a Recurrent Procurement Type? : Yes https://in-tendhost.co.uk/universityofsouthampton/aspx/