Genome Plasmid
University Of Edinburgh · Scotland
Key facts
- Contract value
- USN 75,135
- Awarded
- 14 Aug 2025
- Procedure
- Open procedure
- Buyer type
- Education
Awarded to
| Supplier | Value |
|---|---|
| Indiana University | USN 75,135 |
Description
We are planning a clinical trial to treat a rare genetic disease that causes progressive dementia in children. Our therapy is based on the following: Autologous haematopoietic stem progenitor cells (HSPCs) are modified ex vivo with a lentiviral vector (LV) to express supraphysiologic levels of a secreted enzyme in myeloid progeny, in essence using gene-modified monocytes/macrophages as a durable and effective vehicle for central nervous system (CNS) enzyme delivery. In order to progress this therapy, we require the following; a plasmid to our specification, produced to FDA, IND ready standard for use in the manufacture of a lentiviral vector for clinical trial. This Plasmid will be delivered directly from the supplier to the University of Edinburgh’s partner in the project, University of California Los Angeles.
Categories (CPV)
- 33140000 Medical consumables
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