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Tenfell
Awarded contract
Published 04 Apr 2017

Supply of Biomarkers of Vaccine Protection in Murine Model of Btb

Defra Network eTendering Portal · United Kingdom

Key facts

Contract value
£24,000
Awarded
12 Dec 2016
Contract starts
07 Dec 2016
Contract ends
30 Apr 2017
Procedure
Award of contract without prior publication of a contract notice
Buyer type
Central government

Awarded to

SupplierValue
National Institute for Biological Standards and Control (NIBSC)£24,000

Description

Objective 1. Characterisation of BCG-Induced protective cells. By characterizing the incomplete immunity induced by BCG, we may be able to design improved vaccines which stimulate better or additional long term memory responses. A prerequisite for this is more tractable measurement of long term memory responses in cattle, and understanding BCG protection in mice is an optimal approach to achieve this. One of the approaches being undertaken is RNA-Seq & combined bio-informatic analysis on highly specific T cells from immune mice, isolated by flow cytometric sorting.

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