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Tenfell
Awarded contract
Published 24 Oct 2025

LIONNS-D2 Project - Production of T3S API, IMP and FDF

Cardiff University · Wales

Key facts

Contract value
€953,600
Awarded
21 Oct 2025
Contract starts
06 Nov 2025
Contract ends
31 Jan 2027
Procedure
Direct award
Buyer type
Education

Awarded to

SupplierValue
Ardena Holding NV€953,600

Description

Cardiff University's School of Medicine is procuring the manufacture of a novel investigational medicinal product (IMP), Triiodothyronine sulphate (T3S), for use in a Phase 2b clinical trial. The service includes the production of the active pharmaceutical ingredient (API), the IMP, and the finished drug formulation (FDF) in blister packs. This bespoke drug is intended for hypothyroid patients with a specific genetic variation affecting thyroid hormone metabolism. The supplier will manufacture the product to GMP standards, using a validated Route of Synthesis supported by existing preclinical and toxicology data.

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